IL-4-PE, 4D9, 2 mL, ASR

Product No:IM2719U

Interleukin-4 (IL-4) is a monomeric 20 kDa predominantly produced by activated T lymphocytes of the Th2 phenotype, by mast cells and by some antigen-presenting cells. Together with IL-2, IL-4 is an autocrine growth factor for activated T cells and for cytotoxic T cell precursors. IL-4 is a major factor involved in the activation of resting B lymphocytes. Together with IL-13, IL-4 induces isotype switch towards IgE and IgG1 isotypes. Activated CD4+ T cells of the Th1 phenotype produce predominantly IL-2 and Interferon γ, whereas CD4+ T cells of the Th2 phenotype produce IL-4, IL-5, IL6 and IL-10.

$581.90 List Price - $581.90

Product Specifications

Target Species Human
Specificity IL-4
Other Names IL-4, interleukin-4
Fluorochrome PE
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone 4D9
Isotype IgG1 Mouse
Clone Description The 4D9-PE-conjugated antibody is optimized for flow cytometric detection of intracellular IL-4 in stimulated peripheral mononuclear cells (PBMC) after permeabilizing with formaldehyde / saponin-based IntraPrep Permeabilization Reagent.

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