CD95-PE, UB2, 50 Tests, RUO

Product No:IM1739

The CD95 (Fas or APO-1) antigen is a 40-50 kDa transmembrane glycoprotein. It belongs to the Tumor Necrosis Factor (TNF) superfamily and contains three cysteine-rich repeats. This cell surface molecule mediates apoptosis (programmed cell death). CD95 antigen is expressed on a substantial proportion of peripheral blood CD4+ lymphocytes, CD8+ lymphocytes and B lymphocytes but on a minor proportion of NK cells. It is not found on platelets or erythrocytes, but is expressed variably on granulocytes and monocytes. CD95 is strongly up-regulated on activated T cells, B cells, NK cells and thymocytes. Moreover, it is widely expressed on cell lines of T, B, NK and myeloid lineages. Most other tissues express CD95.

Product Specifications

Target Species Human
Specificity CD95
Other Names APO-1, CD95, Fas, TNFRSF6
Fluorochrome PE
Regulatory Status RUO
Size 50 Tests
Format Liquid
Clone UB2
Isotype IgG1 Mouse
Cross Reactivity Carp

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