CD66b-APC, 80H3, 0.5 mL, ASR

Product No:B15091

The CD66 antigens were originally described as granulocyte-specific activation antigens, related to the carcino-embryonic antigen (CEA) previously described on colon cancer cells. The CEA/CD66 gene group belongs to the immunoglobulin (Ig) gene superfamily. Among the CD66 cluster, CD66b (also known as CGM6) is a glycosyl-phosphatidylinositol (GPI)-anchored glycoprotein of 95-100 kDa. CD66b is thought to play a role in the regulation of the adhesive activity of CD11/CD18 via signal transduction in neutrophils. It is strongly expressed by myelocytes, metamyelocytes, neutrophils and polymorphonuclear neutrophils. CD66b is weakly expressed by promyelocytes.

Product Specifications

Target Species Human
Specificity CD66b
Other Names CD66b, CEA family, CGM6, NCA-95
Fluorochrome APC
Regulatory Status ASR
Size 0.5 mL
Format Liquid
Flow Product Line IOTest
Clone 80H3
Isotype IgG1 Mouse
Clone Description The 80H3 antibody does not react with peripheral lymphocytes and monocytes.

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