CD37-PE, BL14, 2 mL, ASR

Product No:IM0458

The CD37 antigen is a 40-52 kDa single chain transmembrane protein with 4 transmembrane domains (Tetraspan/TM4SF). This molecule has both its NH2- and COOH-termini inside the cells, and is heavily glycosylated on one extracellular loop. The main feature of this antigen is its high content of hydrophobic residues (45%). The CD37 antigen is strongly expressed on the surface of human peripheral blood B lymphocytes and on B lymphocytes from germinal centers. In the ontogeny of B cells, this antigen appears late, after the pre-B stage, and is not expressed on plasma cells. The CD37 antigen has a low expression on T lymphocytes, granulocytes, and monocytes. A weak reactivity is observed with other cellular types such as Langerhans cells, macrophages, normal medullar granulous cells and peripheral blood polymorphonuclear cells. CD37 is involved in signal transduction.

$547.70 List Price - $547.70


Product Specifications

Target Species Human
Specificity CD37
Other Names CD37, gp40-52
Fluorochrome PE
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone BL14
Isotype IgG1 Mouse

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