CD3-APC, UCHT1, 100 Tests, CE

Product No:IM2467

CD3ζ see TCRζ in Human non-CD antigens section. The CD3 antigen is a complex of 5 invariable polypeptidic chains, γ, δ, ε, ζ and η, whose molecular weights are respectively 25-28, 21, 20, 16 and 22 kDa. The ζ chain occurs in the CD3 complex as a disulphide linked homodimer or as a heterodimer with the η chain. CD3 is part of a bigger complex which includes the T Cell Receptor (TCR). This complex is expressed by mature T cells and by thymocytes. T cell activation may be induced when a foreign antigen is presented to the TCR through MHC complex.

Product Specifications

Target Species Human
Specificity CD3
Fluorochrome APC
Regulatory Status CE
Size 100 Tests
Format Liquid
Flow Product Line IOTest
Clone UCHT1
Isotype IgG1 Mouse
Clone Description UCHT1 reacts with the ε-chain of the CD3 complex. It was used as a CD3 reference mAb (ref.6T-CD3.1) during HLDA 6. After permeabilization with saponin-based permeabilization reagent IntraPrep, it may be used to detect intracytoplasmic CD3 by flow cytometry.

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