CD3-UNLB, UCHT1, 0.2 mg, ASR
Product No:IM1304
CD3ζ see TCRζ in Human non-CD antigens section.
The CD3 antigen is a complex of 5 invariable polypeptidic chains, γ, δ, ε, ζ and η, whose molecular weights are respectively 25-28, 21, 20, 16 and 22 kDa. The ζ chain occurs in the CD3 complex as a disulphide linked homodimer or as a heterodimer with the η chain. CD3 is part of a bigger complex which includes the T Cell Receptor (TCR). This complex is expressed by mature T cells and by thymocytes. T cell activation may be induced when a foreign antigen is presented to the TCR through MHC complex.
$337.50 List Price - $337.50
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Product Specifications
| Target Species | Human |
| Specificity | CD3 |
| Other Names | CD3 |
| Fluorochrome | UNLB |
| Regulatory Status | ASR |
| Size | 0.2 mg |
| Format | Freeze-dried |
| Clone | UCHT1 |
| Isotype | IgG1 Mouse |
| Clone Description | UCHT1 reacts with the ε-chain of the CD3 complex. It was used as a CD3 reference mAb (ref.6T-CD3.1) during HLDA 6. After permeabilization with saponin-based permeabilization reagent IntraPrep, it may be used to detect intracytoplasmic CD3 by flow cytometry. |