CD28-APC, CD28.2, 0.5 mL, ASR
Product No:B10244
The CD28 antigen (Tp44) is a homodimer of disulfide-linked chains, with a molecular weight of 44 kDa each. CD28 antigen is expressed by a majority of CD3+ T lymphocytes. CD4+ T lymphocytes express the CD28 antigen more frequently than do CD8+ T lymphocytes. CD28 antigen is also present on plasma cells and thymocytes. This antigen is involved in the adhesion of T lymphocytes with B lymphocytes, through the B7/BB-1 (CD80) or B70/B7-2 (CD86) glycoproteins and provides a major co-stimulatory signal for T cell activation.
$675.00 List Price - $675.00
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Product Specifications
Target Species | Human |
Specificity | CD28 |
Other Names | CD28, CD80/CD86 Ligand, Tp44 |
Fluorochrome | APC |
Regulatory Status | ASR |
Size | 0.5 mL |
Format | Liquid |
Flow Product Line | IOTest |
Clone | CD28.2 |
Isotype | IgG1 Mouse |
Clone Description | The CD28.2 monoclonal antibody costimulates T cell proliferation and cytokine production in the presence of T cell activators (αCD3, PMA, SEB). It inhibits proliferation of CD4+ T lymphocytes. It cross-reacts with Rhesus monkey peripheral blood lymphocytes. |