CD25-APC-A700, B1.49.9, 50 Tests, CE

Product No:B92454

The CD25 antigen (IL-2Rα chain, Tac or p55) is a single-chain glycoprotein with a molecular weight of 55 kDa which is the low affinity receptor for IL-2 (IL-2Rα). In conjunction with CD122 (IL-2Rβ, p75) and CD132 (IL-2Rγ, p64), CD25 antigen forms the high-affinity IL-2R complex. CD25 antigen is found on activated T and B cells, on activated monocytes and macrophages, and on T cell clones. It is also expressed on NK cells enriched from peripheral blood lymphocytes by culturing in the presence of IL-2. It is absent from thymocytes and resting T and B lymphocytes. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.

Product Specifications

Target Species Human
Specificity CD25
Other Names CD25, IL-2 Receptor, IL-2R1, IL-2Rα, Interleukin (IL)-2 receptor a-chain, p55, TAC
Fluorochrome APC-Alexa Fluor* 700
Regulatory Status CE
Size 50 Tests
Format Liquid
Flow Product Line IOTest
Clone B1.49.9
Isotype IgG2a Mouse
Clone Description The B1.49.9 monoclonal antibody does not block the binding of IL-2 to its receptor.
Cross Reactivity Mink, Ovine, Squirrel Monkey

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