CD1c-PC5.5, L161, 0.5 mL, ASR
Product No:B46036
The CD1c antigen (also called BDCA-1) is a member of the CD1 family of proteins that are structurally related to MHC class I proteins. CD1c is a membrane glycoprotein with a molecular weight of 43 kDa, non-covalently associated with β2-microglobulin. CD1c antigen is expressed on a major subpopulation of human myeloid dendritic cells. In blood, CD1c is also expressed on a subpopulation of CD19+ small resting B lymphocytes. Its expression has also been detected on cortical thymocytes (weakly), on Langerhans cells and on dendritic cells. CD1c+ myeloid dendritic cells have been designated as type-1 myeloid dendritic cells (MDC1s). It has been reported that CD1c is also expressed on mature T cells in a tightly regulated manner. CD1c is involved in antigen-presentation of glycolipids. It may also act in T cells as an immune regulatory molecule.
$639.40 List Price - $639.40
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Product Specifications
Target Species | Human |
Specificity | CD1c |
Other Names | CD1c |
Fluorochrome | PC5.5 |
Regulatory Status | ASR |
Size | 0.5 mL |
Format | Liquid |
Flow Product Line | IOTest |
Clone | L161 |
Isotype | IgG1 Mouse |
Cross Reactivity | Ovine |