CD1a-FITC, BL6, 1 mL, ASR

Product No:B25330

CD1a is a member of the lipid antigen presenting molecules family Like the other CD1 proteins (group 1: CD1a, CD1b, CD1c and group 2: CD1d, CD1e), CD1a is a transmembrane protein of 49 kDa, noncovalently associated with β2-microglobulin. As other group 1 CD1 antigens, CD1a is found on professional antigen-presenting cells (APC) such as dendritic cells, particularly on Langerhans cells and their direct circulating precursors. It is expressed by those cells related to dermal dendritic cells, derived from monocytes cultured for 6 days in the presence of GMCSF and IL-4. The CD1a antigen is also present on a B cell subset. It is also strongly expressed by cortical thymocytes. CD1a antibodies are useful in the definition of the thymic stage of T cells.

Product Specifications

Target Species Human
Specificity CD1a
Other Names CD1a, thymocytes
Fluorochrome FITC
Regulatory Status ASR
Size 1 mL
Format Liquid
Flow Product Line IOTest
Clone BL6
Isotype IgG1 Mouse
Clone Description The BL6 antibody recognizes the C epitope of the CD1a molecule.
Cross Reactivity Equine, Ovine

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