CD183-AF488, G025H7, 0.5 mL, ASR

Product No:B68144

CD183, also called CXCR3, is a 41kDa transmembrane G protein-coupled CXC receptor, belonging to the family of chemokine receptors. It has selectivity for IP10, Mig and I-TAC chemokines. Cellular production of CD183 ligands is induced by interferon, suggesting an important role of CD183 in Th1-type inflammatory processes. CD183 signaling induces chemotactic migration in inflammation-associated effector T cells, involving integrin activation and cytoskeletal changes. CD183 is expressed on T cells (Th1), NK cells, dendritic cells, mast cells, eosinophils. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.

Product Specifications

Target Species Human
Specificity CD183
Other Names CD183, CKR-L2, CXCR3, GPR9, IP10-R, Mig-R
Fluorochrome Alexa Fluor* 488
Regulatory Status ASR
Size 0.5 mL
Format Liquid
Flow Product Line IOTest
Clone G025H7
Isotype IgG1 Mouse

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