CD11c (integrin αX subunit, also known as leucocyte surface antigen p150, Axb2 and CR4) is a member of the integrin family. Like other leucocyte integrins (CD11a, CD11b, CD11d), CD11c is non-covalently associated with the β2 integrin subunit (CD18). CD11c is a transmembrane glycoprotein of 145-150 kDa, mainly expressed by monocytes, macrophages and NK cells, and to a lesser extent by granulocytes, dendritic cells and some subsets of T and B cells.

Specifications

Specificity CD11c
Form PC5
Clone BU15
Flow Product Line IOTest
Clone Description The BU15 antibody was used as a CD11c reference mAb (ref.6) during HLDA 6.
Isotype IgG1 Mouse
Format Liquid
Size 1 mL
Regulatory Status ASR
Target Species Human
Cross Reactivity BU15 cross reacts with: Canine
Other Names a-chain of complement receptor type 4, alphaX, C3bi, C3dg receptor, CD11c, CR4, gp150/95, integrin αX-chain, LeuCAMc
UNSPSC 41116015

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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
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RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.