The CD20 antigen (Bp35) is an integral non-glycosylated membrane protein with four transmembrane domains. Three isoforms (33, 35 and 37 kDa) result from differential phosphorylation within the cytoplasmic domain. The CD20 molecule is present on all normal B lymphocytes from peripheral blood, lymph node, spleen, tonsil and bone marrow but is absent from plasma cells. It is expressed naturally but at low density on a subset of peripheral blood T lymphocytes.

Specifications

Specificity CD20
Form ECD
Clone B9E9
Flow Product Line IOTest
Clone Description All monoclonal antibodies directed to the extracellular domain of the CD20 molecule are likely to bind closely related epitopes.
Isotype IgG2a Mouse
Format Liquid
Size 1 mL
Regulatory Status ASR
Target Species Human
Cross Reactivity B9E9 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Hamadyras Baboon, Olive Baboon, Sooty Mangabey
Other Names Bp35, CD20, membrane-spanning 4-domains
UNSPSC 41116015

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