The CD25 antigen (IL-2Rα chain, Tac or p55) is a single-chain glycoprotein with a molecular weight of 55 kDa which is the low affinity receptor for IL-2 (IL-2Rα). In conjunction with CD122 (IL-2Rβ, p75) and CD132 (IL-2Rγ, p64), CD25 antigen forms the high-affinity IL-2R complex. CD25 antigen is found on activated T and B cells, on activated monocytes and macrophages, and on T cell clones. It is also expressed on NK cells enriched from peripheral blood lymphocytes by culturing in the presence of IL-2. It is absent from thymocytes and resting T and B lymphocytes.

Specifications

Specificity CD25
Form PC5
Clone B1.49.9
Flow Product Line IOTest
Clone Description The B1.49.9 monoclonal antibody does not block the binding of IL-2 to its receptor.
Isotype IgG2a Mouse
Format Liquid
Size 1 mL
Regulatory Status ASR
Target Species Human
Cross Reactivity B1.49.9 cross reacts with: Squirrel Monkey. B1.49.9 cross reacts with: Ovine, Mink
Other Names CD25, IL-2 Receptor, IL-2R1, IL-2Rα, Interleukin (IL)-2 receptor a-chain, p55, TAC
UNSPSC 41116015

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No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.