The CD157 antigen (BST-1) is a highly glycosylated, glycosyl-phosphatidylinositol (GPI)-anchored membrane protein with a molecular weight of 43 kDa. The amino acid sequence of human BST-1 has 33% identity with CD38. As with CD38, BST-1 displays ADP ribosyl cyclase activity and facilitates pre-B cell growth. CD157 antigen is expressed on monocytes, neutrophils and all lymphoid and myeloid precursors. Its expression is restricted to certain fractions (CD44-CD25+ and CD44-CD25-) of CD3-CD4-CD8- T progenitors.

Specifications

Specificity CD157
Form FITC
Clone RF3
Clone Description The RF3 antibody reacts with an external epitope of BST-1 on several human cell lines including certain bone marrow stromal cell, human umbilical vein endothelial cell (HUVEC) and U937 cell lines.
Isotype IgG Mouse
Format Liquid
Size 0.05 mg
Regulatory Status RUO
Target Species Human
Other Names BP-3/IF7, BST-1, cADPr hydrolase 2, CD157, CD38-like, Mo5
UNSPSC 41116015

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