CD83, or HB15 molecule, is a 43 kDa glycoprotein member of the immunoglobulin superfamily. It is composed of a single extracellular V-type Ig-like domain, a transmembrane region and a 40 amino acid cytoplasmic domain. CD83 is predominantly expressed by dendritic lineage cells including Langerhans cells, skin and peripheral blood dendritic cells. It is also expressed by interdigitating reticulum cells present in the T cell zones of lymphoid organs as well as being weakly expressed by some germinal center lymphocytes. CD83 is expressed by in vitro generated dendritic cells. It is not expressed by resting peripheral blood leucocytes at detectable levels and is only expressed at low levels following lymphocyte activation in vitro.

Specifications

Specificity CD83
Form PE
Clone HB15a
Flow Product Line IOTest
Isotype IgG2b Mouse
Format Liquid
Size 2 mL
Regulatory Status ASR
Target Species Human
Cross Reactivity HB15a cross reacts with: Indian Rhesus, Squirrel Monkey
Other Names CD83, HB15
UNSPSC 41116015

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PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS

The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.