The CD154 antigen (CD40-ligand), also known as TRAP (Tumor necrosis factor Related Activation Protein), is a member of the Tumor Necrosis Factor (TNF) superfamily. It is a 32 kDa type II transmembrane molecule. CD154 molecule is induced on the surface of activated T cells, mainly on CD4+ T lymphocytes. This ligand for the CD40 molecule is present on some basophils and mast cells. It has critical regulatory roles in T- and B-lymphocyte function.

Specifications

Target Species Human
Specificity CD154
Other Names CD154, CD40 Ligand, CD40L, T-BAM, TNF-related activation protein 1, TRAP
Fluorochrome PE
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone TRAP-1
Isotype IgG1 Mouse
Clone Description The TRAP-1 antibody inhibits activation induced by full-length soluble human CD154.
Cross Reactivity TRAP-1 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Hamadyras Baboon, Olive Baboon

Technical Documents

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