The CD116 antigen, a 75-85 kDa molecule, is the human Granulocyte-Monocyte Colony-Stimulating Factor (GM-CSF) receptor α chain. The CD116 antigen is not expressed by lymphocytes, but strongly by monocytes and granulocytes as well as their precursors. It is also present on endothelial cells, fibroblasts and Langerhans cells. CD116 associates with the common β chain (CDw131) of the IL-3 and IL-5 receptors to form a high affinity receptor for GM-CSF.

Specifications

Specificity CD116
Form PE
Clone SCO6
Flow Product Line IOTest
Clone Description The SCO6 antibody recognizes an epitope of the GM-CSF receptor α chain. It is a high affinity antibody which binds to the membrane and to the soluble form of GM-CSFR. It immunoprecipitates the molecule. SCO6 antibody does not work in Western Blot assays.
Isotype IgG1 Mouse
Format Liquid
Size 100 Tests
Regulatory Status RUO
Target Species Human
Other Names CD116, GM-CSF receptor alpha subunit, GM-CSFR
UNSPSC 41116015

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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.