The CD49e antigen is the 160 kDa integrin α5-chain, which is composed of a heavy chain (135 kDa) and a light chain (25 kDa), linked by a disulfide bond. CD49e is non-covalently associated with the 130 kDa integrin β1-chain (CD29 molecule), forming the VLA-5 complex. CD49e is expressed by monocytes, platelets and two myeloid cell lines (U937, K562). It is known as the fibronectin and invasin receptor. It is useful for basic studies of fibronectin-mediated adhesion.

Specifications

Specificity CD49e
Form FITC
Clone SAM1
Flow Product Line IOTest
Isotype IgG2b Mouse
Format Liquid
Size 2 mL
Regulatory Status ASR
Target Species Human
Other Names CD49e, Integrin alpha 5 chain, Integrin α5-chain, VLA-5, VLA-alpha5-chain
UNSPSC 41116015

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