The CD35 antigen is a polymorphic molecule. Different molecular weights: 160, 190, 220, 250 and 285 kDa were reported for the various allotypes. It is known as the Complement Receptor type I (CR1) with affinity for C3b, C4b and iC3b. The CD35 antigen is expressed by granulocytes (except basophils), B lymphocytes, monocytes, some NK cells and erythrocytes. The CD35 antigen mediates phagocytosis of complement coated particles.

Specifications

Specificity CD35
Form FITC
Clone J3D3
Flow Product Line IOTest
Clone Description The J3D3 monoclonal antibody inhibits CR1-mediated decay of cells bound to the alternative and classical pathways to C3-convertase sites. It also inhibits C3b dependent rosette formation with lymphocytes.
Isotype IgG1 Mouse
Format Liquid
Size 100 Tests
Regulatory Status RUO
Target Species Human
Other Names C3b/C4b receptor, CD35, complement receptor type 1, CR1
UNSPSC 41116015

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No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.