CD18 is the 95 kDa integrin β2-chain which forms non-covalently-bound heterodimers with the integrin α subunits: CD11a, CD11b and CD11c (αL, αM and αX, respectively). CD18 is expressed by all leucocytes , activated platelets and megakaryocytic cell lines.

Specifications

Target Species Human
Specificity CD18
Other Names CD18, integrin β2-chain, LFA-β chain, Mac-1, macrophage antigen 1, ß2-Integrin chain
Fluorochrome PE
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone 7E4
Isotype IgG1 Mouse
Clone Description 7E4 is a blocking monoclonal antibody in cell adhesion assays.
Cross Reactivity 7E4 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Hamadyras Baboon, Olive Baboon. 7E4 cross reacts with: Bovine, Ovine, Porcine, Equine, Canine, Feline, Mink, Llama

Technical Documents

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PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS

The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.