HLA-DR molecules are found on antigen-presenting cells (APC), i.e. dendritic cells, B lymphocytes, monocytes, macrophages, and thymic epithelial cells. They are also expressed on activated T cells, but not on granulocytes, platelets, or red blood cells. Resting T cells or endothelial cells that do not normally express these molecules can be induced to express them.

Specifications

Target Species Human
Specificity HLA-DR
Other Names HLA Class II, HLA-DR
Fluorochrome FITC
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone B8.12.2
Isotype IgG2b Mouse
Clone Description HLA-DR antibodies are specific to non polymorphic determinants of human HLA class II DR molecules which are constituted of α and B polypeptides of 34 and 29 kDa respectively.
Cross Reactivity B8.12.2 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Olive Baboon, Common Marmoset, Cotton-topped Tamarin, Squirrel Monkey

Technical Documents

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PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS

The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.