The CD2 antigen (LFA-2) is a monomeric 50 kDa glycoprotein. It was formerly described as the sheep red blood cell receptor, causing T-cell rosetting, and has been identified as the ligand for CD58 (LFA-3). It is also a receptor for CD48, CD59 and CD15, which binds to the multimeric form of CD2. CD2 is present on the majority of normal human peripheral blood T lymphocytes and a high percentage of NK cells. It is also expressed by all thymocytes.

Specifications

Target Species Human
Specificity CD2
Other Names CD2, CD58 Ligand, LFA-2, Sheep red blood cell rosettes
Fluorochrome FITC
Regulatory Status ASR
Size 2 mL
Format Liquid
Flow Product Line IOTest
Clone 39C1.5
Isotype IgG2a Rat
Clone Description 39C1.5 inhibits sheep erythrocyte rosette formation. It has been used as a CD2 reference monoclonal antibody during HLDA 6 (ref 6T-CD2.7).
Cross Reactivity 39C1.5 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Hamadyras Baboon, Olive Baboon. 39C1.5 cross reacts with: Equine

Technical Documents

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