CD305, also called LAIR1 (Leucocyte-associated Ig-like receptor 1), is a 31 kDa type 1 transmembrane molecule with a single N terminal extracellular Ig superfamily C2 domain. The extracellular domain contains one N-glycosylation site. CD305 is expressed on the majority of lymphocytes, NK cells, monocytes, dendritic cells and naïve B cells. It inhibits cell cytotoxicity, cell activation, proliferation and differentiation by phosphorylation of its cytoplasmic ITIM motifs.

Specifications

Specificity CD305
Form PE
Clone NKTA255
Flow Product Line IOTest
Isotype IgG1 Mouse
Format Liquid
Size 1 mL
Regulatory Status ASR
Target Species Human
Other Names CD305, LAIR1
UNSPSC 41116015

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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.