CD52, also called CAMPATH-1, is a 21-28 kDa glycopeptide anchored to the membrane by a glycosylphosphatidylinositol (GPI) structure. The mature CD52 antigen is a very small protein (12 aminoacids) of 8-9 kDa. CD52 is expressed on lymphocytes, monocytes, macrophages and on epithelial cells of male reproductive tract, shed into seminal plasma and acquired by spermatozoa. Physiological role of CD52 on lymphocytes is unclear, although CAMPATH-1 antibody is capable of complement activation and it has been used in lympho proliferative disorders. Monoclonal antibodies directed against sperm may cause sperm immobilization and agglutination.

Specifications

Specificity CD52
Form PC7
Clone HI186
Flow Product Line IOTest
Isotype IgG2b Mouse
Format Liquid
Size 0.5 mL
Regulatory Status ASR
Target Species Human
UNSPSC 41116015

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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.