The CD57 antigen (HNK-1 antigen carbohydrate moiety) is an oligosaccharide with sulfated glucoronic acid residues that may be linked to a variety of polypeptides or lipids. In peripheral blood, it is found on a subset of cells with natural killer activity. It is confined to mononuclear cells, primarily large granular lymphocytes. Many of these CD57+ cells co-express the CD8 antigen and are a subset of the suppressor / cytotoxic T lymphocytes. Cord blood T cells or NK cells lack the CD57 antigen. It is not expressed on red blood cells or on platelets but is present on some neuroectodermal tissues.

Specifications

Specificity CD57
Form FITC
Clone NC1
Flow Product Line IOTest
Isotype IgM Mouse
Format Liquid
Size 100 Tests
Regulatory Status CE
Target Species Human
Other Names CD57, HNK-1
UNSPSC 41116015

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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
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RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
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No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.