CLEC9A is a group V C-type lectin receptor (CTLR) comprised of a single extracellular C-type lectin domain (CTLD) connected to the transmembrane domain by a stalk region and an intracellular cytoplasmic tail. In humans, CLEC9A is expressed on the cell surface of a subset of Dendritic cells (DCs) and a subset of CD14+CD16- Monocytes. In dendritic cells, CLEC9A is selectively expressed on CD141+ (BDCA3+) dendritic cells. As opposed to other DC markers, CLEC9A presents the advantage of being expressed in both human and mouse DCs. Thus, it can serve as a DC marker crossing species barriers and may help in the translation from the mouse DC system to human immunobiology.

Specifications

Specificity CD370
Form APC
Clone 8F9
Flow Product Line IOTest
Isotype IgG2a Mouse
Format Liquid
Size 0.5 mL
Regulatory Status ASR
Target Species Human
Other Names CD370, Clec9A
UNSPSC 41116015

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No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.