The CD79a molecule (MB-1, Igα) is part of the MB-1/B29 (CD79a/CD79b) disulfide-linked heterodimer which is non-covalently associated with membrane immunoglobulins (Igs) to build the B Cell antigen Receptor (BCR) complex. CD79a is a 40-45 kDa glycoprotein and belongs to the Ig superfamily of surface antigens. CD79a protein is specifically and strictly expressed throughout B lymphocyte differentiation. It appears early in ontogeny, probably before expression of cytoplasmic μ-chain, and is present in the cytoplasm of plasma cells.

Specifications

Specificity CD79a
Form APC
Clone HM47
Flow Product Line IOTest
Clone Description The HM47 antibody is recommended to be used in flow cytometry after permeabilization with saponin-based permeabilization reagent IntraPrep. The HM47 antibody reacts with a cytoplasmic epitope of the CD79a molecule.
Isotype IgG1 Mouse
Format Liquid
Size 100 Tests
Regulatory Status CE
Target Species Human
Cross Reactivity HM47 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Chimpanzee, Olive Baboon
Other Names BCR complex, CD79a, Iga, Ig alpha, MB-1
UNSPSC 41116015

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IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
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No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.