The CD62L antigen, also called LECAM-1, L-selectin or LAM-1, is a 75 kDa molecule. It acts as the peripheral lymph node homing receptor. It is also involved in lymphocyte binding to High Endothelial Venules (HEV) and in lymphocyte rolling on activated endothelium. CD62L is expressed by B and T lymphocytes, monocytes, neutrophils, eosinophils, and approximately half of the peripheral NK lymphocytes.

Specifications

Specificity CD62L
Form APC
Clone DREG56
Flow Product Line IOTest
Clone Description In contrast to other antibodies recognizing this molecule, DREG56 is particularly effective in blocking CD62L mediated lymphocyte binding to lymph node HEV. DREG56 (ref.33) was used as a CD62L reference monoclonal antibody during the HLDA 6.
Isotype IgG1 Mouse
Format Liquid
Size 0.5 mL
Regulatory Status ASR
Target Species Human
Cross Reactivity DREG56 cross reacts with: Chimpanzee. DREG56 cross reacts with: Bovine
Other Names CD62L, LAM-1, LECAM-1, L-selectin
UNSPSC 41116015

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