The CD44 antigens are transmembrane glycoproteins and members of the hyaladherin family of hyaluronan-binding proteins. Multiple CD44 isoforms have been described, the predominant form being CD44S, a glycoprotein of 85 kDa. CD44 is present on most cells or tissues, but not on platelets, hepatocytes, cardiac muscle, kidney tubular epithelium, testis and skin portions. The human blood group antigens Ina/b reside on CD44. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.

Specifications

Target Species Human
Specificity CD44
Other Names CD44, ECMR-III, gp80-95, H-CAM, Hermes antigen, HUTCH-I, Pgp-1
Fluorochrome APC-Alexa Fluor* 750
Regulatory Status ASR
Size 0.5 mL
Format Liquid
Flow Product Line IOTest
Clone J.173
Isotype IgG1 Mouse
Clone Description J.173 antibody does not inhibit the binding of hyaluronate to its receptor. It can trigger IL-2-dependent proliferation and cytotoxicity of human T cell clones in vitro.

Technical Documents

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No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.