The CD66 antigens were originally described as granulocyte-specific activation antigens, related to the carcino-embryonic antigen (CEA) previously described on colon cancer cells. The CEA/CD66 gene group belongs to the immunoglobulin (Ig) gene superfamily. Among the CD66 cluster, CD66b (also known as CGM6) is a glycosyl-phosphatidylinositol (GPI)-anchored glycoprotein of 95-100 kDa. CD66b is thought to play a role in the regulation of the adhesive activity of CD11/CD18 via signal transduction in neutrophils. It is strongly expressed by myelocytes, metamyelocytes, neutrophils and polymorphonuclear neutrophils. CD66b is weakly expressed by promyelocytes. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.

Specifications

Specificity CD66b
Form APC-Alexa Fluor* 750
Clone 80H3
Flow Product Line IOTest
Clone Description The 80H3 antibody does not react with peripheral lymphocytes and monocytes.
Isotype IgG1 Mouse
Format Liquid
Size 0.5 mL
Regulatory Status ASR
Target Species Human
Other Names CD66b, CEA family, CGM6, NCA-95
UNSPSC 41116015

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IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
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No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.