The CD127 antigen is the human IL-7 receptor α chain. It is a 75-80 kDa molecule. CD127 is found on normal B cell precursors but not on mature B lymphocytes. It is also expressed by the majority of T lymphocytes, a subset of monocytes and a subset of CD34+ cells. CD127 associates with CD132 (IL-2Rγ) to form the high affinity IL-7 receptor. Receptor expression is down-regulated following T cell activation. *Alexa Fluor and Pacific Blue are registered trademarks of Molecular Probes, Inc.

Specifications

Specificity CD127
Form APC-Alexa Fluor* 700
Clone R34.34
Flow Product Line IOTest
Clone Description The R34.34 antibody inhibits binding of IL-7 to CD127.
Isotype IgG1 Mouse
Format Liquid
Size 0.5 mL
Regulatory Status ASR
Target Species Human
Cross Reactivity R34.34 cross reacts with: Indian Rhesus, Pigtailed Macaque
Other Names CD127, IL-7 receptor alpha chain, IL-7R alpha, interleukin-7 receptor, p90
UNSPSC 41116015

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