The CD106 antigen, VCAM-1 (Vascular Cell Adhesion Molecule-1), is an adhesion molecule which binds to integrin α4/β1 (VLA-4) and integrin α4/β7 on lymphocytes. It is a 110 kDa membrane protein. CD106 antigen is present on activated endothelial cells, tissue macrophages, dendritic cells and bone marrow fibroblasts. It is involved in the adhesion of lymphocytes, monocytes and eosinophils to activated endothelium.

Specifications

Specificity CD106
Form PE
Clone 1G11
Flow Product Line IOTest
Clone Description The 1G11 antibody inhibits T lymphocyte adhesion to TNF-stimulated endothelial cells.
Isotype IgG1 Mouse
Format Liquid
Size 100 Tests
Regulatory Status RUO
Target Species Human
Other Names CD106, vascular cell adhesion molecule-1, VCAM-1
UNSPSC 41116015

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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
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RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
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No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.