The CD106 antigen, VCAM-1 (Vascular Cell Adhesion Molecule-1), is an adhesion molecule which binds to integrin α4/β1 (VLA-4) and integrin α4/β7 on lymphocytes. It is a 110 kDa membrane protein. CD106 antigen is present on activated endothelial cells, tissue macrophages, dendritic cells and bone marrow fibroblasts. It is involved in the adhesion of lymphocytes, monocytes and eosinophils to activated endothelium.

Specifications

Target Species Human
Specificity CD106
Other Names CD106, vascular cell adhesion molecule-1, VCAM-1
Fluorochrome PE
Regulatory Status RUO
Size 100 Tests
Format Liquid
Flow Product Line IOTest
Clone 1G11
Isotype IgG1 Mouse
Clone Description The 1G11 antibody inhibits T lymphocyte adhesion to TNF-stimulated endothelial cells.

Technical Documents

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