The CD43 antigen is a 95-135 kDa heavily O-glycosylated and sialylated single chain membrane glycoprotein. This cell surface mucin-type glycoprotein is also called leukosialin or sialophorin. CD43 antigen is expressed by platelets and by all leucocytes, weakly on resting B lymphocytes but highly after activation. A soluble form of CD43 (galactoglycoprotein) can be detected in plasma. This form is produced by proteolytic shedding of the extracellular portion of the membrane molecule after cell activation.

Specifications

Specificity CD43
Form PE
Clone DFT1
Flow Product Line IOTest
Clone Description The DFT1 antibody reacts with an extracellular epitope of the CD43 antigen. It is useful for detecting leucocytes by flow cytometry and immunohistochemistry on routinely-fixed and parrafin-embedded tissue sections. The DFT1 antibody is also able to induce homotypic adhesion of leucocytes.
Isotype IgG1 Mouse
Format Liquid
Size 2 mL
Regulatory Status ASR
Target Species Human
Cross Reactivity DFT1 cross reacts with: Cynomolgus Monkey, Indian Rhesus, Olive Baboon. DFT1 cross reacts with: Ovine
Other Names CD43, gp95, gpL115, leukocyte sialoglycoprotein, Leukosialin, sialophorin
UNSPSC 41116015

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