The CD62P antigen (P-selectin/GMP-140/PADGEM) is a member of the selectin family. Like other selectins (CD62E and CD62L), CD62P contains an amino terminal lectin-like domain, followed by an EGF domain, nine short consensus repeats (SCR), a transmembrane domain and a short cytoplasmic domain. CD62P (140 kDa) is present in megakaryocytes, in Weibel-Palade bodies of endothelial cells and in α-granules of platelets. CD62P is translocated to the surface membrane upon in vitro and in vivo activation. CD62P is involved in the interaction between activated platelets and with monocytes and neutrophils.

Specifications

Specificity CD62P
Form FITC
Clone CLBThromb/6
Flow Product Line IOTest
Clone Description The CLB-Thromb/6 antibody recognizes the boundary region between the lectin and EGF-like domains, which is preserved after platelet fixation. It inhibits platelet adhesion to eosinophils in cell adhesion assays.
Isotype IgG1 Mouse
Format Liquid
Size 100 Tests
Regulatory Status CE
Target Species Human
Other Names CD62P, GMP140, granule membrane protein-140, LECAM-3, PADGEM, P-selectin
UNSPSC 41116015

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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.