The CD19 antigen (also called B4) is a type I membrane glycoprotein with a molecular weight of 95 kDa. CD19 is involved in the regulation of B lymphocyte development, activation and differentiation. This molecule is expressed on all normal B lymphocytes including pro-B lymphocytes. It is also found on the surface of follicular dendritic cells, on the early cells of myelomonocytic lineage and on most stabilized B cell lines. It is not present on normal T lymphocytes, NK cells, monocytes, and granulocytes.

Specifications

Specificity CD19
Form ECD
Clone J3-119
Flow Product Line IOTest
Clone Description In vitro studies show that the CD19 antibodies have an inhibitory effect on the activation and proliferation of B lymphocytes. They also inhibit the B cell response after co-stimulation by anti-immunoglobulin and interleukin 4.
Isotype IgG1 Mouse
Format Liquid
Size 100 Tests
Regulatory Status CE
Target Species Human
Other Names B4, Bgp95, CD19
UNSPSC 41116015

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PRODUCT AVAILABILITY AND REGULATORY STATUS DEPENDS ON COUNTRY REGISTRATION PER APPLICABLE REGULATIONS

The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.