The CD22 antigen (BL-CAM) is a transmembrane glycoprotein of the immunoglobulin superfamily. It may be expressed as two different isoforms: the α form (130 kDa) and the β form (140 kDa). CD22 antigen is a B cell restricted antigen expressed in the cytoplasm of B cell progenitors and on the surface of mature B lymphocytes. CD22 expression is lost after B-cell activation, prior to the plasma cell stage. It is absent from peripheral blood T lymphocytes, granulocytes, monocytes.

Specifications

Specificity CD22
Form RD1
Clone HD239
Flow Product Line cyto-stat
Clone Description The B3 antibody binds to an epitope located within the first Ig-like domain of CD22 antigen. It can be used to detect intracytoplasmic CD22 in flow cytometry after permeabilization.
Isotype IgG2b Mouse
Format Liquid
Size 0.5 mL
Regulatory Status ASR
Target Species Human
Other Names Bgp135, BL-CAM, CD22, Siglec2
UNSPSC 41116015

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No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.