CD1a is a member of the lipid antigen presenting molecules family Like the other CD1 proteins (group 1: CD1a, CD1b, CD1c and group 2: CD1d, CD1e), CD1a is a transmembrane protein of 49 kDa, noncovalently associated with β2-microglobulin. As other group 1 CD1 antigens, CD1a is found on professional antigen-presenting cells (APC) such as dendritic cells, particularly on Langerhans cells and their direct circulating precursors. It is expressed by those cells related to dermal dendritic cells, derived from monocytes cultured for 6 days in the presence of GMCSF and IL-4. The CD1a antigen is also present on a B cell subset. It is also strongly expressed by cortical thymocytes. CD1a antibodies are useful in the definition of the thymic stage of T cells.

Specifications

Specificity CD1a
Form RD1
Clone SFCI19Thy1A8
Flow Product Line coulter clone
Clone Description T6 (ref 6T-CD1.7) was used as a CD1a reference monoclonal antibody during HLDA 6.
Isotype IgG1 Mouse
Format Liquid
Size 100 Tests
Regulatory Status RUO
Target Species Human
Other Names CD1a, thymocytes
UNSPSC 41116015

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