Dry Stimulation Mixes for Immune Functional Assays. Phorbol-Myristate-acetate (PMA) and Ionomycin are broad cellular activators of human leukocytes. Brefeldin A blocks Golgi-apparatus-mediated secretion. A mix of these 3 compounds strongly activates leukocytes and traps newly synthesized biomolecules (e.g. cytokines) inside the cell, hence it can serve e.g. as positive control for leukocyte (ligand-specific) functional assays and as a nonspecific activator in leukocyte functional subtyping experiments.

Specifications

Specificity Phorbol-Myristate-acetate (PMA) / Ionomycin / Brefeldin A
Flow Product Line DuraClone
Format Liquid
Size 25.00|Tests

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