The DuraClone 3 4 G Reagent Kit is a two color immunofluorescence staining reagent for the enumeration of the absolute counts of the total T-lymphocytes (CD3+) and helper/inducer (CD4+) T-Cells. This reagent is intended for flow cytometry based analysis in lysed human whole blood samples, and is recommended for use on the Guava® Personal Cell Analysis (PCA) System. The DuraClone 3 4 G Reagent Kit contains fluorescently labeled antibodies that bind to CD3 and CD4 antigens found on the surface of circulating leukocytes in peripheral blood samples. The CD3 antigen is a complex of six proteins known collectively as the T-cell receptor (TCR) complex. The antibody used in this reagent binds to the 20 kDa ε chain of this complex. The CD4 antigen is a 59 kDa protein. It interacts with class II molecules of the Major Histocompatibility Complex (MHC) and is the primary receptor for the Human Immunodeficiency Virus (HIV). Cells that are CD3+ and CD4+ are identified as helper/inducer lymphocytes. Decreased CD4+CD3+ cell counts have been associated with some forms of immunodeficiency.

Specifications

Specificity CD3-PE-Dy649/CD4-PE
Format Dry
Size 50 Tests
Regulatory Status RUO
UNSPSC 41116015

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The listed regulatory status for products correspond to one of the below:
IVD: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
ASR: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
CE: Products intended for in vitro diagnostic use and conforming to European Directive (98/79/EC). (Note: Devices may be CE marked to other directives than (98/79/EC)
RUO: Research Use Only. These products are labeled "For Research Use Only. Not for use in diagnostic procedures."
LUO: Laboratory Use Only. These products are labeled "For Laboratory Use Only."
No Regulatory Status: Non-Medical Device or non-regulated articles. Not for use in diagnostic or therapeutic procedures.