ProteomeLab XL-A/XL-I

Beckman Coulter pioneered the field of analytical ultracentrifugation and continues to design and produce powerful, reliable, and durable instrumentation to enable academic and industrial research around the world.

By measuring proteins as interacting elements, ProteomeLab XL-A and XL-I systems accelerate the development of diagnostic markers and therapeutic targets for efficient and reliable protein characterization in solution.

Each ProteomeLab system is designed to put actionable information in your hands quickly and easily.




Analytical Ultracentrifugation (AUC)

  • AUC remains the most versatile, rigorous and accurate means for determining the molecular weight and hydrodynamic/thermodynamic properties of a protein or other macromolecule.
  • No other technique is capable of providing the same range of information with a comparable level of precision and accuracy.

Provides data which can answer more critical questions than any other comparable technique, including:

  • Shape
  • Mass
  • Diameter
  • Stoichiometry
  • Heterogeneity
  • Association
  • Aggregation
  • Purity
  • Formulation

Analyzes a wide array of particles in native, matrix-free conditions, including:

  • Proteins
  • Nanoparticles
  • Peptides
  • Polymers
  • Micelles
  • Liposomes
  • Extracellular vesicles
  • Drug conjugates
  • Viral payload

Molecular weight determination

  • The analytical ultracentrifuge is unsurpassed for directly measuring molecular weights of solutes in their native state and as they exist in solution without relying on calibration or making assumptions concerning shape

Product Specifications

Max Speed 50,000 rpm
Max g Force 289848 x g
Acceleration 5-400 rpm/second (above 500 rpm), 400 max acceleration
Deceleration 5-400 rpm/second (above 500 rpm), 400 (max deceleration)
Speed Control ± ±20 rpm of set speed (above 1,000 rpm)
Timed Run 1 to 999 hrs, 59 mins (including hold runs)
Max Capacity Volume Range 0 - 0.4 mL
Operating System(s) LINUX
Max Heat Dissipation 1 kW
Speed Display Actual rotor speed in 10 rpm increments (below 1,000 rpm) & 100 rpm increments (above 1,000 rpm)
Temperature Control 0.50 °C of set temperature after equilibration
Display 15.3" high-resolution color touch screen
Time (Actual Display) Real-time run monitoring, time elapsed or time remaining (hold run)
Temperature Range(s) Set temperature range: 0 to 40°C in 1°C increments, Rotor temperature after equilibration: ±0.5°C of set temperature, Displayed rotor temperature after equilibration: ±0.3°C of set temperature
Item Specifications Referenced 969340


  • Filter by:
Title Description