Annexin V-FITC/7-AAD kit (7-AAD kit)
Flow Product Type:
In the early phase of apoptosis, the integrity of cell membrane is maintained but the cells lose membrane phospholipid asymmetry. Phosphatidylserine (PS), a negatively charged phospholipid located in the inner leaflet of the plasma membrane, is then exposed at the cell surface. Annexin V, which is a calcium and phospholipid binding protein, binds preferentially to PS. The ANNEXIN V kits are apoptosis detection kits, based on the binding properties of conjugated annexin V to PS, in combination to propidium iodide (PI) staining. Apoptotic cells stained by a simple, quick (10 minutes) one-step staining procedure with the Annexin V-FITC kit. No fixation of the cells is necessary. The stained cells may be analyzed by fluorescence micropscopy or flow cytometry.
: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
: CE-marked products. CE-marked products are labeled for in vitro diagnostic use and can be traded throughout the EU.
: Research Use Only Reagents. These reagents are labeled "For Research Use Only. Not for use in diagnostic procedures."
: Laboratory Use Only Reagents. These reagents are labeled "For Laboratory Use Only."
IVD & CE
: In Vitro Diagnostic Products and CE-Marked Products. These reagents comply with the IVD and CE classifications and are distributed worldwide for in vitro diagnostic use.
ASR & RUO
: Analyte Specific Reagents & Research Use Only Reagents. These reagents are labeled ASR for distribution throughout the Americas and RUO throughout the rest of the world. These products comply with the ASR and RUO definitions above.