Flow Product Line:
Flow Product Type:
The APO2.7 antigen (also named 7A6 antigen) recognized by clone 2.7A6A3 is a 38 kDa protein localized on the membrane of mitochondria whose expression appears to be restricted to cells undergoing apoptosis. The APO2.7 antigen can be detected after apoptosis induction via CD95/Fas ligation, irradiation or drug treatment. Expression of APO2.7 appears as an early event in the apoptosis process. Normal viable cells are negative or weakly positive for APO2.7. Research studies have shown that less than 2% of peripheral T cells from normal donors expressed APO2.7 antigen. Some level of APO2.7 expression associated with an on-going apoptotic process was demonstrated in activated T cells.
: In Vitro Diagnostic Products. These products are labeled "For In Vitro Diagnostic Use."
: Analyte Specific Reagents. These reagents are labeled "Analyte Specific Reagents. Analytical and performance characteristics are not established."
: CE-marked products. CE-marked products are labeled for in vitro diagnostic use and can be traded throughout the EU.
: Research Use Only Reagents. These reagents are labeled "For Research Use Only. Not for use in diagnostic procedures."
: Laboratory Use Only Reagents. These reagents are labeled "For Laboratory Use Only."
IVD & CE
: In Vitro Diagnostic Products and CE-Marked Products. These reagents comply with the IVD and CE classifications and are distributed worldwide for in vitro diagnostic use.
ASR & RUO
: Analyte Specific Reagents & Research Use Only Reagents. These reagents are labeled ASR for distribution throughout the Americas and RUO throughout the rest of the world. These products comply with the ASR and RUO definitions above.