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Matt Maloney, Beckman Coulter, Inc. Beckman Coulter began shipping its new DTX Series Multimode Detectors to customers in June, 2004. The new DTX Series Multimode Detectors provide unmatched value and flexibility for a variety of application and automation needs. Capable of performing fluorescence (intensity, polarization and time-resolved), glow luminescence and absorbance measurements on the same instrument, the DTX Series can operate as standalone instruments or can be integrated seamlessly with Beckman Coulter's Biomek® Laboratory Automation Workstations. The DTX Series is ideal for a broad range of Systems Biology applications, including drug discovery, genomics, proteomics and cell-based research. The unique optics design, featuring high-power light-emitting diode (LED) light sources, ensures precise performance and sensitivity across all detection modes. The instruments facilitate easy integration with automated liquid handling systems via a choice of plate loading options, including an extra-wide plate access door, and accepting plates in portrait or landscape formats. In addition, the detector's intuitive software platform provides instrument control and easy protocol development, as well as compatibility with Beckman Coulter's Biomek and SAMI® software. The DTX 800 features fluorescence intensity (top reading), absorbance (visible) and glow luminescence for 96- to 384-well plates, as well as linear and orbital shaking, while the DTX 880 features fluorescence intensity (top and bottom reading), time-resolved fluorescence, fluorescence polarization, absorbance (UV and visible), glow luminescence and temperature control for 6- to 1536-well plates. In addition, the instrument also features linear and orbital shaking, plus temperature control. The flexibility and sensitivity of the DTX Multimode Detectors has been successfully demonstrated by our customers at Chiron, Merck, Massachusetts General Hospital, Scripps Research Institute and the National Institutes of Health (NIH), to name a few. They have demonstrated the utility of the DTX detectors in a variety of Systems Biology and automated applications, including:
The DTX Multimode Detectors are also part of the new Biomek Assay Workstation, which has been optimized for cell-based screening and ELISAs. The new Assay Workstation can be configured with either the Biomek FX or the Biomek NX liquid handlers, providing multiple pipetting and configuration options to accommodate customer needs for different capacity, throughput and lab space requirements.
Additional Information: For comments or questions about T3 Update, please contact David Daniels, Ph.D., editor.
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