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Biomek® Multichannel Tip Pipetting

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The Biomek® Multichannel Tip Pipetting solution utilizes a 96- or 384- channel head to enable customers to perform serial dilutions in either single or multiple columns or rows. This solution is available on both the Biomek FX and Biomek NX and consists of both custom software steps and custom Multichannel Pod Receivers. For a description of the Serial Dilution Step, see "A Custom Serial Dilution Step" in the November 2004 issue of the T³ Update.

This solution is supported on Biomek software version 3.2 and Biomek FX software version 2.5e, and supports any 96- or 384 well plate already supported by the Biomek software (Figure A). It allows for either a full or partial box of tips to be loaded, even accommodating tip boxes pre-configured by the user.

To date, there have been over 80 shipments of the Biomek Multichannel Tip Pipetting solution to customers including GlaxoSmithKline, Amgen, Amphora, Applied Biosystems, AstraZeneca, Aventis, Boehringer Ingelheim, Bristol Myers Squibb, Merck, Novartis, Novozymes, Organon, Pfizer, Procter and Gamble, Roche, and Scynexis, to name a few. The solution can generally be shipped in about four weeks once the order is received.

Custom Software Steps Include:

Serial Dilution with Select Tips Step (Figure B)
Unload Select Tips Step
Load Select Tips Step
Aspirate with Select Tips Step
Dispense with Select Tips Step
Mix with Select Tips Step
96-Channel Configurations
-Column 1, Columns 1 & 7, Row 1
384-Channel Configurations
-Column 1, Columns 1 & 13, Row 1

Custom Multichannel Pod Receivers Allow:

Loading of a full box of tips
Loading of a partial box of tips
Tip box pre-configured by the user
Single column
Single row (Figure C)
Multiple columns
Multiple rows (Figure D)

Figure A. The screen shot shows the default options for tip loading that is available with software installation. Additional configurations may be customized for your installation.

Figure B. The customer specification can be made in the Serial Dilution with Select Tips Step.

Figure C. Row 1 in a 96-channel head

Figure D. Rows 1 and 13 on 384-channel head

The custom Multichannel Pod Modified Receiver enables single or multiple rows or columns of tips to be loaded, from a full, partial, or preconfigured tip box. Unlike the previous solution, the loading of a full box is not initially required.

For Research Use Only; not for use in diagnostic procedures.

Additional Information:

For comments or questions about T³Update, please contact David Daniels, Ph.D., editor.