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The automated methods we provide for our customers, scientists in Academia, Small Biotech and Large BioPharma, have been developed to two different levels of development: Verified and Validated Solutions. Verified Solutions are applications that have been developed by customers, chemistry partner chemistry companies or by groups internal to Beckman Coulter that have been verified to work on the Biomek® family of liquid handlers by our Applications team. These verified solutions illustrate the flexibility of the Biomek liquid handling platform and provide a robust solution. They are provided as a template for customers to modify to their specific needs. Validated Solutions are applications that have been fully developed by the Beckman Coulter
Applications team to work on a specific Biomek liquid handling platform. The platform has been optimized for the performance of that specific application. This fully validated turn-key solution addresses a key step or constraint in the research processes our customers deal with on a daily basis. The full support infrastructure of Beckman Coulter stands behind these validated solutions. In this issue of the T3 Update newsletter you will find verified solutions in the following sections: Applications: In this section we provide you with application notes and/or poster presentations of automated solutions on the Biomek family of liquid handlers that will provide you with verified solutions. Integrated Solutions: In this section we provide you with the latest Automated Labware Positioners (ALPs) and software capabilities available for integration onto our automation platforms (e.g., Assay Workstation and SAGIAN™ Core systems). These solutions have been developed by our SAGIAN team of hardware and software engineers. Contact your local Beckman Coulter sales associate if you see an ALP you'd like to have integrated on your system. Project Management – NAO: In this section we share the latest integration projects developed for a customer by our team of integration experts in North America Operations (NAO). This team works with the Integrated Solutions team at SAGIAN to solve a particular automation challenge for a customer. While most of these projects involve large automation systems some of the solutions may be applicable to you. Customer Training and Support: In this section we share a letter from a satisfied customer of the training received from our Customer Training and Support (CTS) team in NAO. The CTS team provides training courses at three sites in North America and has recently developed a new online capability: eLab Live On-line, which facilitates live Biomek FX training over the web. Check us out! FAQs: In this section we provide you with a description of our world class support team which has the charter to guide you through resolution of challenges faced when you apply Beckman Coulter automation. Event Calendar: In this section we provide you with an update of scheduled events related to automation around the globe: trade shows, user group meetings, etc. As I said earlier, it is my goal to provide you with Tips, Tricks and Techniques in the T3 Update newsletter that keep you on track for delivering robust assays that deliver reliable answers to the biological questions posed by your research. Let me know if I've accomplished this goal. Do you have questions I've not yet addressed? This is your forum!
About the editor: My academic training was focused on transcriptional regulation in prokaryotic systems. I defined the essential elements in overlapping promoter DNA sequences in E. coli (Ph.D. in Biology, U.C. Irvine, 1981-1987) and defined specific amino acid – nucleotide contacts made between a developmentally regulated sigma subunit of RNA polymerase and its cognate promoter DNA in B. subtilis (post-doc, Harvard Biolabs, 1987-1991). I left academia to join Beckman Instruments in December 1991, with a goal to develop an alternative DNA amplification technology that did not infringe on PCR. We successfully achieved that goal by developing a DNA ligase-dependent amplification of DNA that could amplify target molecules >106 fold through thermal cycling (PCT/US93/07342). I made a career move off the lab bench to provide technical evaluation of key technologies that enable drug discovery research and provide strategic planning for delivery of those technologies to Beckman Coulter customers. I now hold the title of Applications Marketing Manager. I am responsible for converting assay kits from a manual to an automated format on liquid handlers in the Biomek continuum. I work in Fullerton, Calif., as part of the Platforms and Automation Business Center. -- David W. Daniels, Ph.D. For comments or questions about T3 Update, please contact David Daniels, Ph.D., editor.
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