Sneak Peek of Workshop Talks

Lab Automation 2008, January 27–30, Palm Springs, CA

Automation and Detection of a GPCR Functional Assay
( In association with Cisbio-US, Inc – IP-One HTRF* Assay )
When: January 28, 2008 at 12:30 pm - 2:00 pm
Where: Room - Smoketree D and E

Beckman Coulter, Inc.
200 S Kraemer Blvd.
Brea California 92822
www.beckman.com

Inositol phosphate 1 (IP1) is a direct metabolite of IP3 which accumulates in cells following Gq recepetor activation and is stable in the presence of LiCl making it an ideal marker for a GPCR (Gq) functional assay.

In collaboration with Cisbio, Beckman Coulter has automated the IP-One* HTRF assay along with detection and analysis using the Beckman Coulter Biomek® Laboratory Automation Workstation and PARADIGM™ Detection Platform.

This workshop will discuss the details of the IP-One assay, PARADIGM™ Detection Platform and automation methods and results.

Integration of High-Throughput Laboratory Automation and Cell Culture Process Monitoring Technologies
(In association with Genentech, Inc.)
When: January 29, 2008 at 12:30 pm - 2:00 pm
Where: Room - Smoketree D and E

Genentech, Inc.
1 DNA Way
South San Francisco, CA, 94080
www.gene.com

Large-scale suspension mammalian cell culture present challenges to the currently existing laboratory automation technology to improve efficiency of bioprocess development. The Biomek FX Laboratory Automation Workstation was employed to prepare reagents and media in TubeSpin* tubes and 96-well plates. A high-throughput osmometer, a flow cytometer and a pH meter were developed and integrated with the Biomek® FX. This system is designed to deliver throughputs at least ten times higher than typical shake flask systems.

This workshop will:

1.	Introduce automated Liquid Handling in Process Development
2.	Describe configuration of automation with detection technology that improve cell culture process development
3.	Discuss new software features to enhance sample processing, data tracking, data mining and data archiving