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In this world of specialization, no one company can develop the entire portfolio of automated applications that will satisfy your evolving research needs. To extend our offering, and so better support your needs, Beckman Coulter has partnered with several chemistry companies, including Sigma-Aldrich, Invitrogen, Millipore and Promega to provide automated applications derived from manual kits they’ve developed. In support of these partnerships, Beckman Coulter has leveraged its strength in automation hardware and software to unify the Biomek family of Liquid Handlers to run on the same operating software package (Biomek software, version 3.2). You now have the opportunity to use the same tools to adopt these methods or develop your own on any of the Biomek platforms, including the Biomek 3000, the NX (Multichannel or Span-8), the FX and Assay Workstation (NX or FX). Further, assay applications can be readily moved from one Biomek platform to another as your throughput needs change. At Lab Automation 2005, Beckman Coulter hosted an Applications Automation Workshop where we presented new applications that have been developed by the Beckman Coulter Applications teams in Fullerton, CA and Indianapolis, IN and our partners at Sigma Aldrich, Invitrogen, Millipore and Promega. These applications have been developed as either verified or fully validated application solutions. Verified solutions are applications that have been developed and verified to work on one or more Biomek platforms by our Applications team. These verified solutions illustrate the flexibility of the Biomek liquid handling platform and provide a robust solution. They are provided as a template for customers to modify to their specific needs. Conversely, fully validated solutions are developed and optimized for performance on a specific platform. These fully validated turnkey solutions address a key step or constraint in the research process for our customers. The full support infrastructure of Beckman Coulter stands behind these validated solutions. All of the presentations given at the Workshop by Beckman Coulter and those of our partners (with permission from each of the respective parties) are provided for you in this issue of T3 Update. I have also included all of the related poster materials that were shown at the Lab Automation 2005 show for your convenience. For additional information, feel free to contact me or visit the websites of our chemistry partner companies Sigma-Aldrich, Invitrogen, Millipore and Promega regarding the verified solutions their applications teams have developed for the Biomek platforms. Please contact your local Beckman Coulter representative for the availability of these solutions in your area. Have I provided you with the Tips, Tricks and Techniques in the T3 Update newsletter that you need to obtain reliable answers from robust automated assays? Let me know – this is your forum!
About the editor: My academic training was focused on transcriptional regulation in prokaryotic systems. I defined the essential elements in overlapping promoter DNA sequences in E. coli (Ph.D. in Biology, U.C. Irvine, 1981-1987) and defined specific amino acid – nucleotide contacts made between a developmentally regulated sigma subunit of RNA polymerase and its cognate promoter DNA in B. subtilis (post-doc, Harvard Biolabs, 1987-1991). I left academia to join Beckman Instruments in December 1991, with a goal to develop an alternative DNA amplification technology that did not infringe on PCR. We successfully achieved that goal by developing a DNA ligase-dependent amplification of DNA that could amplify target molecules >106 fold through thermal cycling (PCT/US93/07342). I made a career move off the lab bench to provide technical evaluation of key technologies that enable drug discovery research and provide strategic planning for delivery of those technologies to Beckman Coulter customers. I now hold the title of Applications Marketing Manager. I am responsible for converting assay kits from a manual to an automated format on liquid handlers in the Biomek continuum. I work in Fullerton, Calif., as part of the Platforms and Automation Business Center. -- David W. Daniels, Ph.D. For comments or questions about T3 Update, please contact David Daniels, Ph.D., editor.
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