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Automated tandem repeat analysis
Because of their high degree of heterozygosity and simple
methodology, short tandem repeats--including PCR* amplification,
fragment sizing and locus/allele scoring--have become one of the
most widely used genomic markers. The CEQ™ 8800 software provides
accurate and high-precision sizing of the amplified fragments,
including automated allele and locus identification. It's able to
identify alleles even in the presence of polymerase artifacts such
as sturter and plus A peaks.
Since all parameters associated with
results are at your fingertips, data can be reviewed with ease. The
electropherograms may be further stacked and overlaid to facilitate
comparison.
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to enlarge image
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| Our powerful and intuitive Binning
Software simplifies the creation of Locus Tags.
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to enlarge image
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| The STR Genotype Summary report can be
exported for linkage/association studies. In addition, automated
analysis of loss heterozygosity (LOH)/microsatellite instability
(MI) or phylogenetic analysis can be
achieved.
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to enlarge image
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The CEQ 8800 delivers high-precision DNA fragment sizing across
capillary arrays, gels and instruments.
Expected Allele
Size (bases)
Observed Sizes |
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196 |
277 |
281 |
403 |
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Across
Instruments |
Mean
S.D. |
196.19
0.05 |
278.59
0.24 |
282.68
0.24 |
402.47
0.21 |
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Across
Arrays |
Mean
S.D. |
196.13
0.18 |
278.58
0.19 |
282.66
0.19 |
402.40
0.15 |
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Across
Gels |
Mean
S.D. |
195.98
0.08 |
278.54
0.15 |
282.62
0.15 |
402.13
0.27 |
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Across All
Variables |
Mean
S.D. |
196.10
0.12 |
278.57
0.20 |
282.65
0.20 |
402.33
0.26 |
* All trademarks are the property of their respective owners. Where applicable,
the PCR process is covered by patents owned by Roche Molecular Systems, Inc.,
and F. Hoffmann-LaRoche, Ltd.
For Research Use Only; not for use in diagnostic procedures. 
Additional GenomeLab™ Information:
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